Monika Fuxreiter

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Biography

MSc. Chemistry, Eötvös Loránd University (Budapest, 1993)
PhD. Chemistry, Eötvös Loránd University (Budapest, 1996)
DSc. Biology, Hungarian Academy of Sciences (Budapest, 2013)


Post-doctoral research
1996 University of Southern Californa, Los Angeles (Arieh Warshel)
1997-98 Rutgers University, New Brunswick (Helen Berman)
1998-2000 Mount Sinai School of Medicine, New York (Roman Osman)


Professional record
2000-2010 Institute of Enzymology, Hungarian Academy of Sciences (Budapest)
2010-2011 Weizmann Institute of Science (Rehovot, Israel)
2011 University of Cambridge, Laboratory of Molecular Biology, MRC (Cambridge)
2012- University of Debrecen, Department of Biochemistry and Molecular Biology


Honors
2014.  Women scientist of the year
2014.  Bagossi Peter award
2012.  Momentum award, Hungarian Academy of Sciences
2009.  L’Oreal-Unesco prize, ”Women in science”
2009.  Bolyai Gold medal
2007.  Pro Scientia Gold Laureate (supervisor)
2005.  Bolyai fellowship
2004.  New England Biolabs Prize
2003.  Academic Young scientist prize
2001.  Bolyai fellowship
1998.  Bio-Science prize
1995.  Young scientist prize, Biochemical Society
1993.  Pro Scientia Gold Laureate
1993.  Nívó Prize


Selected publications
Wu H, Fuxreiter M. (2016) The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules. Cell. 165(5):1055-1066.  abstract

Sharma R, Raduly Z, Miskei M, Fuxreiter M. (2015) Fuzzy complexes: Specific binding without complete folding. FEBS Lett. 589, 2533-42.  abstract

M. Fuxreiter, L. Mones (2014) The role of reorganization energy in rational enzyme design. Curr Opin Chem Biol. 21C:34-41.  abstract

M. Buljan, G. Chalancon, S. Eustermann, G. Wagner, M. Fuxreiter, A. Bateman, M.M. Babu (2012) Tissue-specific splicing of disordered segments that embed binding motifs rewires protein interaction networks. Mol Cell 46, 871-883.  abstract

M Fuxreiter (2012) Fuzziness: linking regulation to protein dynamics. Mol Biosystems  8, 168-177.  abstract

M. Fuxreiter, P. Tompa (2012) Fuzzy complexes: a more stochastic view of protein function. Adv Exp Med Biol. 2012;725:1-14  abstract

M.Fuxreiter, I. Simon, S. Bondos (2011) Dynamic protein-DNA recognition: beyond what can be seen. Trends in Biochem Sci 36, 415-423.  abstract

A Toth-Petroczy, I Simon M Fuxreiter, Y Levy (2009) Disordered tails of homeodomains facilitate DNA recognition by providing a trade-off between folding and specific binding. J Am Chem Soc 131, 15084-85   abstract

M Fuxreiter, P Tompa, I Simon, VN Uversky, JC Hansen, F Asturias (2008) Malleable machines take shape in eukaryotic transcription regulation. Nat Chem Biol 4, 728-737  abstract

P. Tompa and M Fuxreiter (2008) Fuzzy complexes: polymorphism and structural disorder in protein–protein interactions.Trends in Biochem. Sci 33, 2-8  abstract

M. Fuxreiter, P. Tompa, I. Simon (2007) Local structural disorder imparts plasticity on linear motifs. Bioinformatics 23, 950-956.  abstract

M. Fuxreiter, I. Simon, P. Friedrich and P. Tompa (2004) Preformed structural elements feature in partner recognition by intrinsically unstructured proteins. J. Mol. Biol. 338, 1015-1026.  abstract


Scientific activities
2009 DNA enzymes MCRTN meeting organizer
2014 Gordon Conference IDP vice-chair
2016 Gordon Conference IDP chair